Archive for the ‘Non-Small-Cell’ Category

PET imaging response a prognostic factor after thoracic radiation therapy for lung cancer

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A rapid decline in metabolic activity on a PET scan after radiation therapy for non-small cell lung cancer is correlated with good local tumor control, according to a study presented by researchers at Thomas Jefferson University Hospital at the 51st ASTRO Annual Meeting.
In addition, the researchers also found that the higher the metabolic activity and tumor size on a PET scan before treatment, the more likely a patient is to die from lung cancer.

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What are the Real Benefits Versus Risks of Preventative Brain Radiation for Patients With Non-Small Cell Lung Cancer?

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Patients with non-small cell lung cancer treated with preventative brain radiation (called prophylactic cranial irradiation or PCI), significantly decrease their risk of developing brain metastases (cancer spread in the brain) by more than 50 percent (from 18 percent to 8 percent), compared to those who did not receive the treatment, according to a randomized study presented at the plenary session November 2, 2009, at the 51st Annual Meeting of American Society for Radiation Oncology (ASTRO).

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Stereotactic Radiotherapy Stops Lung Cancer From Growing in Frail Patients

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Stereotactic body radiation therapy (SBRT) stopped the growth of cancer at its original site in the lung for three years among nearly 98 percent of patients with early non-small cell lung cancer (NSCLC) who are unable to have the cancer surgically removed, according to an updated three-year study presented November 2, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO).

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Preventative Brain Radiation for Lung Cancer Patients: The Benefits and Risks

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A new study is taking a closer look at the benefits versus risks for lung cancer patients to undergo preventative brain radiation therapy as a means to stop cancer from spreading to the brain.
Study results show that while preventative brain radiation for patients with non-small cell lung cancer – the most common form of lung cancer – does reduce the chance of developing brain metastases, it impacts some short-term and long-term memory.

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Novel therapy may eradicate lung cancer

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Scientists from UT Southwestern Medical Center have suggested a novel therapeutic strategy that would completely eradicate lung cancer.
Researchers Pier Paolo Scaglioni and Georgia Konstantinidou have shown that using an investigative drug called BEZ235 in combination with low-dose radiation successfully eliminated non-small cell lung (NSCL) cancer in mice.

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TNM lung cancer classification needs fine tuning

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NEW YORK (Reuters Health) – Some lung cancer patients classified as T3 by the new TNM classification, seventh edition should be redefined as T2b, say researchers from The University of Texas M. D. Anderson Cancer Center in Houston.
“Outcome prediction should be individualized for each patient,” Dr. Edward S. Kim told Reuters Health. “Even within one stage, tumor and patients characteristics may help identify individuals who will have better outcome, and thus allow us to tailor treatment commensurate with each patient’s prognosis.”

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Lung cancer survival improved by maintenance therapy with pemetrexed

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Giving pemetrexed maintenance therapy to patients with non-small-cell lung cancer (NSCLC) who have not had disease progression after initial platinum-based chemotherapy improves both overall and progression-free survival… More than 1 million people worldwide die every year from lung cancer, and more than 87% of these cases are non-small-cell lung cancer. About 40% of patients have advanced disease at presentation.

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New Drug May Offer Hope to Some With Lung Cancer

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Maintenance therapy with the drug pemetrexed improves the survival of people with non-small-cell lung cancer whose disease has not progressed after chemotherapy, a new study has found.
Nearly 90 percent of all people who die from lung cancer have non-small-cell tumors. At the time the cancer is discovered, it’s considered advanced about 40 percent of the time…

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IntrinsiQ Study: Oncologists Overlook Maintenance Therapy Option – More Often than They Realize

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Surprise Findings from First IntelliView 360 Research Reveal Underserved Cancer
Patient Population
WALTHAM, Mass.–(Business Wire)–
IntrinsiQ, the company improving the quality and understanding of cancer care,
today announced the findings of the company`s first IntelliView 360 research
study. The biggest outcome: Oncologists believe they treat lung cancer patients
in the maintenance setting three times more often than they actually do.This study examines the use of maintenance therapy – an option for metastatic
cancer patients to incrementally extend survival or improve their quality of
life – in treating non-small cell lung cancer (NSCLC).

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Researchers Develop Assay for Predicting Lung Cancer Drug Response

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NEW YORK (GenomeWeb News) – In a paper appearing online today in the journal BMC Cancer, a British-led team of scientists showed that looking at the expression of a set of known or suspected drug response genes may offer clues for choosing the most promising non-small cell lung cancer treatments.

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